Target deconvolution strategies in drug discovery-Reference-Cited by-同舟云学术

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Target deconvolution strategies in drug discovery

Published:2007-11 Issue:11 Volume:6 Page:891-903
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Terstappen Georg C.,Schlüpen Christina,Raggiaschi Roberto,Gaviraghi Giovanni

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd2410.pdf

Reference78 articles.

1. Sneader, W. Drug discovery: a history (John Wiley & Sons, Chichester, UK, 2005).

2. International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 431, 931–945 (2004).

3. Lander, E. S. et al. Initial sequencing and analysis of the human genome. Nature 409, 860–921 (2001).

4. Venter, J. C. et al. The sequence of the human genome. Science 291, 1304–1351 (2001).

5. Overington, J. P., Al-Lazikani, B. & Hopkins, A. L. How many drug targets are there? Nature Rev. Drug Discov. 5, 993–996 (2006). This study examines the results of a comprehensive survey and proposes a consensus number of current drug targets for all classes of therapeutic drugs.

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