Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/nsmb.1642.pdf
Reference39 articles.
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2. Holt, L.J. & Siddle, K. Grb10 and Grb14: enigmatic regulators of insulin action—and more? Biochem. J. 388, 393–406 (2005).
3. Charalambous, M. et al. Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism. Proc. Natl. Acad. Sci. USA 100, 8292–8297 (2003).
4. Smith, F.M. et al. Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life. Mol. Cell. Biol. 27, 5871–5886 (2007).
5. Wang, L. et al. Peripheral disruption of the Grb10 gene enhances insulin signaling and sensitivity in vivo. Mol. Cell. Biol. 27, 6497–6505 (2007).
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