Mechanism of artemisinin resistance for malaria PfATP6 L263 mutations and discovering potential antimalarials: An integrated computational approach-Reference-Cited by-同舟云学术

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Mechanism of artemisinin resistance for malaria PfATP6 L263 mutations and discovering potential antimalarials: An integrated computational approach

Published:2016-07-29 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

N. Nagasundaram,C. George Priya Doss,Chakraborty Chiranjib,V. Karthick,D. Thirumal Kumar,V. Balaji,R. Siva,Lu Aiping,Ge Zhang,Zhu Hailong

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep30106.pdf

Reference56 articles.

1. Klayman, D. L. Qinghaosu (artemisinin): an antimalarial drug from China. Science 228, 1049–1055 (1985).

2. Arrow, K. J., Panosian, C. B. & Geltband, H. Saving Lives, Buying Time. (National Academies Press), doi: 10.17226/11017 (2004).

3. Jefford, C. W. Why artemisinin and certain synthetic peroxides are potent antimalarials. Implications for the mode of action. Curr. Med. Chem. 8, 1803–1826 (2001).

4. Pandey, A. V., Tekwani, B. L., Singh, R. L. & Chauhan, V. S. Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite. J. Biol. Chem. 274, 19383–19388 (1999).

5. Ellis, D. S. et al. The chemotherapy of rodent malaria, XXXIX. Ultrastructural changes following treatment with artemisinine of Plasmodium berghei infection in mice, with observations of the localization of [3H]-dihydroartemisinine in P. falciparum in vitro. Ann. Trop. Med. Parasitol. 79, 367–374 (1985).

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