New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders
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Published:2019-07-29
Issue:9
Volume:3
Page:950-961
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ISSN:2397-3374
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Container-title:Nature Human Behaviour
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language:en
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Short-container-title:Nat Hum Behav
Author:
Evangelou EvangelosORCID, Gao He, Chu Congying, Ntritsos GeorgiosORCID, Blakeley Paul, Butts Andrew R., Pazoki Raha, Suzuki HideakiORCID, Koskeridis FotiosORCID, Yiorkas Andrianos M., Karaman IbrahimORCID, Elliott Joshua, Luo QiangORCID, Aeschbacher Stefanie, Bartz Traci M., Baumeister Sebastian E., Braund Peter S., Brown Michael R., Brody Jennifer A.ORCID, Clarke Toni-Kim, Dimou NikiORCID, Faul Jessica D., Homuth Georg, Jackson Anne U.ORCID, Kentistou Katherine A.ORCID, Joshi Peter K.ORCID, Lemaitre Rozenn N., Lind Penelope A.ORCID, Lyytikäinen Leo-PekkaORCID, Mangino MassimoORCID, Milaneschi Yuri, Nelson Christopher P.ORCID, Nolte Ilja M.ORCID, Perälä Mia-MariaORCID, Polasek Ozren, Porteous DavidORCID, Ratliff Scott M., Smith Jennifer A.ORCID, Stančáková Alena, Teumer AlexanderORCID, Tuominen Samuli, Thériault Sébastien, Vangipurapu Jagadish, Whitfield John B.ORCID, Wood Alexis, Yao Jie, Yu Bing, Zhao WeiORCID, Arking Dan E., Auvinen Juha, Liu Chunyu, Männikkö Minna, Risch Lorenz, Rotter Jerome I.ORCID, Snieder Harold, Veijola Juha, Blakemore Alexandra I., Boehnke MichaelORCID, Campbell Harry, Conen David, Eriksson Johan G., Grabe Hans J.ORCID, Guo Xiuqing, van der Harst PimORCID, Hartman Catharina A., Hayward CarolineORCID, Heath Andrew C., Jarvelin Marjo-Riitta, Kähönen Mika, Kardia Sharon L. R., Kühne Michael, Kuusisto Johanna, Laakso MarkkuORCID, Lahti JariORCID, Lehtimäki Terho, McIntosh Andrew M.ORCID, Mohlke Karen L.ORCID, Morrison Alanna C., Martin Nicholas G.ORCID, Oldehinkel Albertine J.ORCID, Penninx Brenda W. J. H., Psaty Bruce M., Raitakari Olli T., Rudan IgorORCID, Samani Nilesh J., Scott Laura J.ORCID, Spector Tim D., Verweij NiekORCID, Weir David R.ORCID, Wilson James F.ORCID, Levy Daniel, Tzoulaki IoannaORCID, Bell Jimmy D.ORCID, Matthews Paul M.ORCID, Rothenfluh AdrianORCID, Desrivières SylvaneORCID, Schumann GunterORCID, Elliott PaulORCID
Publisher
Springer Science and Business Media LLC
Subject
Behavioral Neuroscience,Experimental and Cognitive Psychology,Social Psychology
Reference87 articles.
1. GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 392, 1015–1035 (2018). 2. Poznyak, V. & Rekve, D. (eds) Global Status Report on Alcohol and Health 2018.
https://www.who.int/substance_abuse/publications/global_alcohol_report/gsr_2018/en/
(WHO, 2018). 3. Wood, A. M. et al. Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. Lancet 391, 1513–1523 (2018). 4. Verhulst, B., Neale, M. C. & Kendler, K. S. The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies. Psychol. Med. 45, 1061–1072 (2015). 5. Schumann, G. et al. KLB is associated with alcohol drinking, and its gene product β-klotho is necessary for FGF21 regulation of alcohol preference. Proc. Natl Acad. Sci. USA 113, 14372–14377 (2016).
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