Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep19312.pdf
Reference66 articles.
1. Kitada, M. & Koya, D. SIRT1 in Type 2 diabetes: mechanisms and therapeutic potential. Diabetes Metab J. 37, 315–325 (2013).
2. Yeung, F. et al. Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23, 2369–2380 (2004).
3. Nemoto, S., Fergusson, M. M. & Finkel, T. SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1α. J Biol Chem. 280, 16456–16460 (2005).
4. Fan, W. & Luo, J. SIRT1 regulates UV-induced DNA repair through deacetylating XPA. Mol cell 39, 247–258 (2010).
5. Brunet, A. et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011–2015 (2004).
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Identification of phytoestrogens as sirtuin inhibitor against breast cancer: Multitargeted approach;Computational Biology and Chemistry;2024-10
2. Targeting Sirtuin 1 for therapeutic potential: Drug repurposing approach integrating docking and molecular dynamics simulations;PLOS ONE;2023-12-20
3. The design and virtual screening of thiourea derivatives as a Sirtuin-1 inhibitor;Pharmacia;2023-11-16
4. Machine Learning-Enabled Genome Mining and Bioactivity Prediction of Natural Products;ACS Synthetic Biology;2023-08-22
5. Mining big data in drug discovery—triaging and decision trees;Big Data Analytics in Chemoinformatics and Bioinformatics;2023
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3