Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation-Reference-Cited by-同舟云学术

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Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation

Published:2016-02-08 Issue:3 Volume:23 Page:217-224
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Yuan Zuanning,Bai Lin,Sun Jingchuan,Georgescu Roxana,Liu Jun,O'Donnell Michael E,Li Huilin

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsmb.3170.pdf

Reference65 articles.

1. Evrin, C. et al. A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. Proc. Natl. Acad. Sci. USA 106, 20240–20245 (2009).

2. Remus, D. et al. Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139, 719–730 (2009).

3. Botchan, M. & Berger, J. DNA replication: making two forks from one prereplication complex. Mol. Cell 40, 860–861 (2010).

4. Yeeles, J.T., Deegan, T.D., Janska, A., Early, A. & Diffley, J.F. Regulated eukaryotic DNA replication origin firing with purified proteins. Nature 519, 431–435 (2015).

5. Moyer, S.E., Lewis, P.W. & Botchan, M.R. Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc. Natl. Acad. Sci. USA 103, 10236–10241 (2006).

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