Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep15649.pdf
Reference33 articles.
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2. Lando, D. et al. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Gene. Dev. 16, 1466–1471; doi: 10.1101/gad.991402 (2002).
3. Ruan, K., Song, G. & Ouyang, G. L. Role of Hypoxia in the Hallmarks of Human Cancer. J. Cell. Biochem. 107, 1053–1062, doi: 10.1002/jcb.22214 (2009).
4. Armitage, E. G., Kotze, H. L. & Williams, K. J. Correlation-based Network Analysis of Cancer Metabolism: A New Systems Biology Approach in Metabolomics. (Springer, 2014).
5. Sonveaux, P. et al. Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J.Clin. Invest. 118, 3930–3942; doi: 10.1172/jci36843 (2008).
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