A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Microbiology (medical),Genetics,Applied Microbiology and Biotechnology,Immunology,Microbiology
Link
http://www.nature.com/articles/s41564-020-0674-4.pdf
Reference49 articles.
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2. Balaji, S. Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains. Nucleic Acids Res. 33, 3994–4006 (2005).
3. Kim, K. The epigenome, cell cycle, and development in Toxoplasma. Annu. Rev. Microbiol. 72, 479–499 (2018).
4. Saksouk, N. et al. Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii. Mol. Cell. Biol. 25, 10301–10314 (2005).
5. Bougdour, A. et al. Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites. J. Exp. Med. 206, 953–966 (2009).
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