Gut-homing Δ42PD1+Vδ2 T cells promote innate mucosal damage via TLR4 during acute HIV type 1 infection
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Microbiology (medical),Genetics,Applied Microbiology and Biotechnology,Immunology,Microbiology
Link
http://www.nature.com/articles/s41564-017-0006-5.pdf
Reference72 articles.
1. Vantourout, P. & Hayday, A. Six-of-the-best: unique contributions of γδ T cells to immunology. Nat. Rev. Immunol. 13, 88–100 (2013).
2. McCarthy, N. E. et al. Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells. J. Immunol. 191, 2752–2763 (2013).
3. McCarthy, N. E. et al. Azathioprine therapy selectively ablates human Vδ2(+) T cells in Crohn’s disease. J. Clin. Invest. 125, 3215–3225 (2015).
4. Brandes, M., Willimann, K. & Moser, B. Professional antigen-presentation function by human γδ T cells. Science 309, 264–268 (2005).
5. Bjarnason, I. et al. Intestinal inflammation, ileal structure and function in HIV. AIDS 10, 1385–1391 (1996).
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