The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets-Reference-Cited by-同舟云学术

The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets

Published:2021-04-27 Issue:7 Volume:6 Page:899-909
ISSN:2058-5276
Container-title:Nature Microbiology
language:en
Short-container-title:Nat Microbiol

Author:

Peacock Thomas P.,Goldhill Daniel H.^ORCID,Zhou Jie,Baillon Laury,Frise Rebecca,Swann Olivia C.,Kugathasan Ruthiran,Penn Rebecca,Brown Jonathan C.,Sanchez-David Raul Y.,Braga Luca,Williamson Maia Kavanagh,Hassard Jack A.,Staller Ecco,Hanley Brian,Osborn Michael,Giacca Mauro^ORCID,Davidson Andrew D.,Matthews David A.^ORCID,Barclay Wendy S.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Microbiology (medical),Genetics,Applied Microbiology and Biotechnology,Immunology,Microbiology

Link

http://www.nature.com/articles/s41564-021-00908-w.pdf

Reference67 articles.

1. Zhou, P. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579, 270–273 (2020).

2. Zhu, N. et al. A novel coronavirus from patients with pneumonia in China, 2019. N. Engl. J. Med. 382, 727–733 (2020).

3. World Health Organisation. WHO Coronavirus Disease (COVID-19) Dashboard https://covid19.who.int/ (2021).

4. Matsuyama, S. et al. Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2. J. Virol. 84, 12658–12664 (2010).

5. Simmons, G. et al. Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry. Proc. Natl Acad. Sci. USA 102, 11876–11881 (2005).

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