Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Microbiology (medical),Genetics,Applied Microbiology and Biotechnology,Immunology,Microbiology
Link
http://www.nature.com/articles/s41564-017-0007-4.pdf
Reference72 articles.
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2. Wells, T. N. C., van Huijsduijnen, R. H. & Van Voorhis, W. C. Malaria medicines: a glass half full? Nat. Rev. Drug Discov. 14, 424–442 (2015).
3. Sinden, R. E. Targeting the parasite to suppress malaria transmission. Adv. Parasitol. 97, 147–185 (2017).
4. Josling, G. A. & Llinás, M. Sexual development in Plasmodium parasites: knowing when it’s time to commit. Nat. Rev. Microbiol. 13, 573–587 (2015).
5. Bousema, T. & Drakeley, C. Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination. Clin. Microbiol. Rev. 24, 377–410 (2011).
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