HIV-2/SIV Vpx targets a novel functional domain of STING to selectively inhibit cGAS–STING-mediated NF-κB signalling-Reference-Cited by-同舟云学术

HIV-2/SIV Vpx targets a novel functional domain of STING to selectively inhibit cGAS–STING-mediated NF-κB signalling

Published:2019-10-28 Issue:12 Volume:4 Page:2552-2564
ISSN:2058-5276
Container-title:Nature Microbiology
language:en
Short-container-title:Nat Microbiol

Author:

Su Jiaming,Rui Yajuan,Lou Meng,Yin Lu,Xiong Hanchu,Zhou Zhenbang,Shen Si,Chen Ting,Zhang Zhengguo,Zhao Na,Zhang Wei,Cai Yong,Markham Richard,Zheng Shu,Xu Rongzhen,Wei Wei,Yu Xiao-Fang^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Microbiology (medical),Genetics,Applied Microbiology and Biotechnology,Immunology,Microbiology

Link

http://www.nature.com/articles/s41564-019-0585-4.pdf

Reference68 articles.

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2. Yu, X. F., Ito, S., Essex, M. & Lee, T. H. A naturally immunogenic virion-associated protein specific for HIV-2 and SIV. Nature 335, 262–265 (1988).

3. Yu, X. F., Yu, Q. C., Essex, M. & Lee, T. H. The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage. J. Virol. 65, 5088–5091 (1991).

4. Goujon, C. et al. SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells. Retrovirology 4, 2 (2007).

5. Mangeot, P. et al. High levels of transduction of human dendritic cells with optimized SIV vectors. Mol. Ther. 5, 283–290 (2002).

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