A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Microbiology (medical),Genetics,Applied Microbiology and Biotechnology,Immunology,Microbiology
Link
http://www.nature.com/articles/s41564-018-0244-1.pdf
Reference40 articles.
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2. Kelly, J. M. et al. Characterization of a human gene inducible by alpha- and beta-interferons and its expression in mouse cells. EMBO J. 5, 1601–1606 (1986).
3. Shresta, S. et al. Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical. J. Virol. 78, 2701–2710 (2004).
4. Schoggins, J. W. et al. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472, 481–485 (2011).
5. Schoggins, J. W. et al. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature 505, 691–695 (2014).
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