The deleterious mutation load is insensitive to recent population history
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://www.nature.com/articles/ng.2896.pdf
Reference30 articles.
1. Coventry, A. et al. Deep resequencing reveals excess rare recent variants consistent with explosive population growth. Nat. Commun. 1, 131 (2010).
2. Marth, G.T. et al. The functional spectrum of low-frequency coding variation. Genome Biol. 12, R84 (2011).
3. Keinan, A. & Clark, A.G. Recent explosive human population growth has resulted in an excess of rare genetic variants. Science 336, 740–743 (2012).
4. Nelson, M.R. et al. An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science 337, 100–104 (2012).
5. Tennessen, J.A. et al. Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science 337, 64–69 (2012).
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