Vectoring siRNA therapeutics into the clinic
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology
Link
http://www.nature.com/articles/nrclinonc.2010.131.pdf
Reference10 articles.
1. Davis, M. E. et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 464, 1067–1070 (2010).
2. Bumcrot, D. et al. RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat. Chem. Biol. 2, 711–719 (2006).
3. Castanotto, D. & Rossi, J. J. The promises and pitfalls of RNAi-interference-based therapeutics. Nature 457, 426–433 (2009).
4. Ferrari, M. Cancer nanotechnology: opportunities and challenges. Nat. Rev. Cancer 5, 161–171 (2005).
5. Xia, H. et al. siRNA mediated gene silencing in vitro and in vivo. Nat. Biotechnol. 20, 1006–1010 (2002).
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