Dysregulated autophagy increased melanocyte sensitivity to H2O2-induced oxidative stress in vitiligo
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep42394.pdf
Reference28 articles.
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3. Schallreuter, K. U. et al. Low catalase levels in the epidermis of patients with vitiligo. J Invest Dermatol 97, 1081–1085 (1991).
4. Schallreuter, K. U. et al. Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(−)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low serotonin and melatonin levels. FASEB J 26, 2457–2470 (2012).
5. Sravani, P. V. et al. Determination of oxidative stress in vitiligo by measuring superoxide dismutase and catalase levels in vitiliginous and non-vitiliginous skin. Indian J Dermatol Venereol Leprol 75, 268–271 (2009).
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