DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

Author:

Woo Richard A.,McLure Kevin G.,Lees-Miller Susan P.,Rancourt Derrick E.,Lee Patrick W. K.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference28 articles.

1. Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B. & Craig, R. W. Participation of p53 in the cellular response to DNA damage. Cancer Res. 51, 6304–6311 (1991).

2. Tishler, R. B., Calderwood, S. K., Coleman, C. N. & Price, B. D. Increases in sequence-specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. Cancer Res. 53, 2212–2216 (1993).

3. Nelson, W. G. & Kastan, M. B. DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell. Biol. 14, 1815–1823 (1994).

4. Anderson, C. W. & Lees-Miller, S. P. The human DNA-activated protein kinase DNA-PK. Crit. Rev. Eukaryot. Gene Expr. 2, 283–314 (1992).

5. Gottlieb, T. M. & Jackson, S. P. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72, 131–142 (1993).

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