Rapid biosynthesis of glycoprotein therapeutics and vaccines from freeze-dried bacterial cell lysates

Author:

Stark Jessica C.ORCID,Jaroentomeechai Thapakorn,Warfel Katherine F.ORCID,Hershewe Jasmine M.,DeLisa Matthew P.ORCID,Jewett Michael C.ORCID

Funder

United States Department of Defense | United States Army | U.S. Army Research, Development and Engineering Command | Army Research Office

American Cancer Society

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Reference59 articles.

1. US Centers for Disease Control and Prevention. Epidemiology and Prevention of Vaccine-Preventable Diseases 13th edn (eds Hamborsky, J., Korger, A. & Wolfe, C.) (Public Health Foundation, 2015).

2. FDA okays marketing of human insulin. Chem. Eng. News Arch. 60, 5 (1982).

3. Mullin, R. Cost to develop new pharmaceutical drug now exceeds $2.5 B. Scientific American https://www.scientificamerican.com/article/cost-to-develop-new-pharmaceutical-drug-now-exceeds-2-5b/ (24 November 2014).

4. Thiel, K. A. Biomanufacturing, from bust to boom…to bubble? Nat. Biotechnol. 22, 1365 (2004).

5. Jayapal, K. P., Wlaschin, K. F., Hu, W. & Yap, M. G. S. Recombinant protein therapeutics from CHO cells-20 years and counting. Chem. Eng. Prog. 103, 40 (2007).

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