Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep36370.pdf
Reference64 articles.
1. de Rooij, J. et al. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature 396, 474–477, doi: 10.1038/24884 (1998).
2. Kawasaki, H. et al. A family of cAMP-binding proteins that directly activate Rap1. Science 282, 2275–2279 (1998).
3. Metrich, M. et al. Epac mediates beta-adrenergic receptor-induced cardiomyocyte hypertrophy. Circ Res 102, 959–965, doi: 10.1161/CIRCRESAHA.107.164947 (2008).
4. Ulucan, C. et al. Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy. Am J Physiol Heart Circ Physiol 293, H1662–H1672, doi: 10.1152/ajpheart.00159.2007 (2007).
5. Yokoyama, U. et al. The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals. Proceedings of the National Academy of Sciences of the United States of America 105, 6386–6391, doi: 10.1073/pnas.0801490105 (2008).
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