Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2−/− mice and human primary sclerosing cholangitis-Reference-Cited by-同舟云学术

Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2−/− mice and human primary sclerosing cholangitis

Published:2018-08-24 Issue:11 Volume:98 Page:1465-1477
ISSN:0023-6837
Container-title:Laboratory Investigation
language:en
Short-container-title:Lab Invest

Author:

Meng Fanyin,Kennedy Lindsey,Hargrove Laura,Demieville Jennifer,Jones Hannah,Madeka Taronish,Karstens Allen,Chappell Kevin,Alpini Gianfranco,Sybenga Amelia,Invernizzi Pietro,Bernuzzi Francesca,DeMorrow Sharon,Francis Heather

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Pathology and Forensic Medicine

Link

http://www.nature.com/articles/s41374-018-0101-0.pdf

Reference44 articles.

1. Williamson KD, Chapman RW. New therapeutic strategies for primary sclerosing cholangitis. Semin Liver Dis. 2016;36:5–14.

2. Halilbasic E, Fuchs C, Hofer H, et al. Therapy of primary sclerosing cholangitis—today and tomorrow. Dig Dis. 2015;33(Suppl 2):S149–63.

3. Popov Y, Patsenker E, Fickert P, et al. Mdr2 (Abcb4)−/− mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes. J Hepatol. 2005;43:1045–54.

4. Trauner M, Fickert P, Wagner M. MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes. Semin Liver Dis. 2007;27:77–98.

5. Jones H, Hargrove L, Kennedy L, et al. Inhibition of mast cell-secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis Mdr2−/− mice. Hepatology. 2016;64:1202–16.

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