Evaluation of Various Static and Dynamic Modeling Methods to Predict Clinical CYP3A Induction Using In Vitro CYP3A4 mRNA Induction Data-Reference-Cited by-同舟云学术

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Evaluation of Various Static and Dynamic Modeling Methods to Predict Clinical CYP3A Induction Using In Vitro CYP3A4 mRNA Induction Data

Published:2013-08-29 Issue:2 Volume:95 Page:179-188
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:
Short-container-title:Clin Pharmacol Ther

Author:

Einolf H J,Chen L,Fahmi O A,Gibson C R,Obach R S,Shebley M,Silva J,Sinz M W,Unadkat J D,Zhang L,Zhao P

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference36 articles.

1. Current Industrial Practices in Assessing CYP450 Enzyme Induction: Preclinical and Clinical

2. In Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America Perspective

3. PREDICTION OF DRUG-DRUG INTERACTIONS FROM IN VITRO INDUCTION DATA

4. A Combined Model for Predicting CYP3A4 Clinical Net Drug-Drug Interaction Based on CYP3A4 Inhibition, Inactivation, and Induction Determined in Vitro

5. Evaluation of models for predicting drug–drug interactions due to induction

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