A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6-Reference-Cited by-同舟云学术

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A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6

Published:2013-04-10 Issue:2 Volume:94 Page:260-268
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:
Short-container-title:Clin Pharmacol Ther

Author:

Machavaram K K,Almond L M,Rostami-Hodjegan A,Gardner I,Jamei M,Tay S,Wong S,Joshi A,Kenny J R

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference38 articles.

1. REGULATION OF DRUG-METABOLIZING ENZYMES AND TRANSPORTERS IN INFLAMMATION

2. Impact of Infectious and Inflammatory Disease on Cytochrome P450–Mediated Drug Metabolism and Pharmacokinetics

3. Cytokines influence mRNA expression of cytochrome P450 3A4 and MDRI in intestinal cells

4. Interleukin-6 and cytochrome-P450, reason for concern?

5. Disease–Drug–Drug Interaction Involving Tocilizumab and Simvastatin in Patients With Rheumatoid Arthritis

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