Evaluation of Various Static In Vitro–In Vivo Extrapolation Models for Risk Assessment of the CYP3A Inhibition Potential of an Investigational Drug-Reference-Cited by-同舟云学术

Evaluation of Various Static In Vitro–In Vivo Extrapolation Models for Risk Assessment of the CYP3A Inhibition Potential of an Investigational Drug

Published:2013-09-18 Issue:2 Volume:95 Page:189-198
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:
Short-container-title:Clin Pharmacol Ther

Author:

Vieira Md L T,Kirby B,Ragueneau-Majlessi I,Galetin A,Chien J Y L,Einolf H J,Fahmi O A,Fischer V,Fretland A,Grime K,Hall S D,Higgs R,Plowchalk D,Riley R,Seibert E,Skordos K,Snoeys J,Venkatakrishnan K,Waterhouse T,Obach R S,Berglund E G,Zhang L,Zhao P,Reynolds K S,Huang S-M

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference33 articles.

1. Drug interactions evaluation: An integrated part of risk assessment of therapeutics

2. Drug Interaction Studies: Study Design, Data Analysis, and Implications for Dosing and Labeling

3. CYP3A4 Substrate Selection and Substitution in the Prediction of Potential Drug-Drug Interactions

4. PREDICTION OF TIME-DEPENDENT CYP3A4 DRUG-DRUG INTERACTIONS: IMPACT OF ENZYME DEGRADATION, PARALLEL ELIMINATION PATHWAYS, AND INTESTINAL INHIBITION

5. The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America

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