Modeling and Simulation of Biopharmaceutical Performance
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Reference12 articles.
1. A compartmental absorption and transit model for estimating oral drug absorption
2. Predicting the impact of physiological and biochemical processes on oral drug bioavailability
3. Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model
4. Evolution of a detailed physiological model to simulate the gastrointestinal transit and absorption process in humans, Part 1: Oral solutions
5. The role of predictive biopharmaceutical modeling and simulation in drug development and regulatory evaluation
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1. System Biology Modeling for Drug Optimization;In Silico Clinical Trials for Cardiovascular Disease;2024
2. Physiologically based biopharmaceutics modeling of regional and colon absorption in humans;European Journal of Pharmaceutics and Biopharmaceutics;2023-05
3. Prediction of In Vitro Drug Dissolution into Fed-state Biorelevant Media: Contributions of Solubility Enhancement and Relatively Low Colloid Diffusivity;European Journal of Pharmaceutical Sciences;2022-06
4. Integration of Engineered Delivery with the Pharmacokinetics of Medical Candidates via Physiology-Based Pharmacokinetics;Methods in Molecular Biology;2022
5. Biopharmaceutics Applications of Physiologically Based Pharmacokinetic Absorption Modeling and Simulation in Regulatory Submissions to the U.S. Food and Drug Administration for New Drugs;The AAPS Journal;2021-02-22
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