Carboxylesterase 1 Polymorphism Impairs Oseltamivir Bioactivation in Humans
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Reference16 articles.
1. Oseltamivir in Seasonal, Avian H5N1 and Pandemic 2009 A/H1N1 Influenza
2. Clinical Pharmacokinetics of the Prodrug Oseltamivir and its Active Metabolite Ro 64-0802
3. The Pharmacokinetics and Tolerability of the Oral Neuraminidase Inhibitor Oseltamivir (Ro 64-0796/GS4104) in Healthy Adult and Elderly Volunteers
4. Anti-Influenza Prodrug Oseltamivir Is Activated by Carboxylesterase Human Carboxylesterase 1, and the Activation Is Inhibited by Antiplatelet Agent Clopidogrel
5. Activation of the Antiviral Prodrug Oseltamivir Is Impaired by Two Newly Identified Carboxylesterase 1 Variants
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