NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/nature06721.pdf
Reference30 articles.
1. Zhai, R. G. et al. Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. PLoS Biol. 4, e416 (2006)
2. MacDonald, J. M. et al. The Drosophila cell corpse engulfment receptor draper mediates glial clearance of severed axons. Neuron 50, 869–881 (2006)
3. Gillingwater, T. H. & Ribchester, R. R. Compartmental neurodegeneration and synaptic plasticity in the WldS mutant mouse. J. Physiol. (Lond.) 534, 627–639 (2001)
4. Mack, T. G. et al. Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene. Nature Neurosci. 4, 1199–1206 (2001)
5. Ribchester, R. R. et al. Persistence of neuromuscular junctions after axotomy in mice with slow Wallerian degeneration (C57BL/WldS). Eur. J. Neurosci. 7, 1641–1650 (1995)
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