Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway-Reference-Cited by-同舟云学术

Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway

Published:2007-09-26 Issue:7163 Volume:449 Page:745-747
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

John Matthias,Constien Rainer,Akinc Akin,Goldberg Michael,Moon Young-Ah,Spranger Martina,Hadwiger Philipp,Soutschek Jürgen,Vornlocher Hans-Peter,Manoharan Muthiah,Stoffel Markus,Langer Robert,Anderson Daniel G.,Horton Jay D.,Koteliansky Victor,Bumcrot David

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature06179.pdf

Reference15 articles.

1. Soutschek, J. et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432, 173–178 (2004)

2. Zimmermann, T. S. et al. RNAi-mediated gene silencing in non-human primates. Nature 441, 111–114 (2006)

3. Song, E. et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nature Med. 9, 347–351 (2003)

4. Grimm, D. et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 441, 537–541 (2006)

5. Narvaiza, I. et al. Effect of adenovirus-mediated RNA interference on endogenous microRNAs in a mouse model of multidrug resistance protein 2 gene silencing. J. Virol. 80, 12236–12247 (2006)

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