Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma-Reference-Cited by-同舟云学术

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Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma

Published:2017-01-05 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Neira José L.,Bintz Jennifer,Arruebo María,Rizzuti Bruno,Bonacci Thomas,Vega Sonia,Lanas Angel,Velázquez-Campoy Adrián,Iovanna Juan L.,Abián Olga

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep39732.pdf

Reference57 articles.

1. Imming, P., Sinnin, C. & Meyer, A. Drugs, their targets and the nature and number of drug targets. Nat. Rev. Drug Discov. 5, 821–834 (2006).

2. Hüser, J. High-throughput screening in drug discovery. In: Methods and Principles in Medicinal Chemistry, Vol. 35 (Wiley-VCH, 2006).

3. Wells, J. A. & McClendon, C. L. Reaching for high-hanging fruit in drug discovery at protein-protein interfaces. Nature 450, 1001–1009 (2007).

4. Uversky, V. N. A decade and a half of protein intrinsic disorder: biology still waits for biophysics. Protein Sci. 22, 693–724 (2013).

5. Tompa, P. Intrinsically disordered proteins: a 10-year recap. Trends Biochem. Sci. 37, 509–516 (2012).

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