Technology Insight: therapeutic RNA interference—how far from the neurology clinic?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Neurology (clinical)
Link
http://www.nature.com/articles/ncpneuro0551.pdf
Reference78 articles.
1. Fire A et al. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806–811
2. Paulson H and Gonzalez-Alegre P (2006) RNAi gets its prize. Lancet Neurol 5: 997–999
3. Gonzalez-Alegre P (2007) Therapeutic RNA interference for neurodegenerative diseases: from promise to progress. Pharmacol Ther 114: 34–55
4. Davidson BL and Paulson HL (2004) Molecular medicine for the brain: silencing of disease genes with RNA interference. Lancet Neurol 3: 145–149
5. Rodriguez-Lebron E and Gonzalez-Alegre P (2006) Silencing neurodegenerative disease: bringing RNA interference to the clinic. Expert Rev Neurother 6: 223–233
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