Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death

Author:

Graham Nicholas A12,Tahmasian Martik12,Kohli Bitika12,Komisopoulou Evangelia12,Zhu Maggie12,Vivanco Igor3,Teitell Michael A4567,Wu Hong2568,Ribas Antoni258910,Lo Roger S2511,Mellinghoff Ingo K31213,Mischel Paul S245,Graeber Thomas G12578

Affiliation:

1. Crump Institute for Molecular Imaging, University of California Los Angeles CA USA

2. Department of Molecular and Medical Pharmacology, University of California Los Angeles CA USA

3. Human Oncology and Pathogenesis Program, Memorial Sloan‐Kettering Cancer Center New York NY USA

4. Department of Pathology and Laboratory Medicine, University of California Los Angeles CA USA

5. Jonsson Comprehensive Cancer Center, University of California Los Angeles CA USA

6. Broad Stem Cell Research Center, University of California Los Angeles CA USA

7. California NanoSystems Institute, University of California Los Angeles CA USA

8. Institute for Molecular Medicine, University of California Los Angeles CA USA

9. Division of Surgical Oncology, Department of Surgery, University of California Los Angeles CA USA

10. Division of Hematology/Oncology, Department of Medicine, University of California Los Angeles CA USA

11. Division of Dermatology, Department of Medicine, University of California Los Angeles CA USA

12. Department of Pharmacology, Weill‐Cornell Medical College New York NY USA

13. Department of Neurology, Memorial Sloan‐Kettering Cancer Center New York NY USA

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

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