Dual silencing of Bcl-2 and Survivin by HSV-1 vector shows better antitumor efficacy in higher PKR phosphorylation tumor cells in vitro and in vivo
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/cgt201530.pdf
Reference41 articles.
1. Jemal A, Siegel R, Xu JQ, Ward E . Cancer Statistics, 2010. CA Cancer J Clins 2010; 60: 277–300.
2. Workenhe ST, Simmons G, Pol JG, Lichty BD, Halford WP, Mossman KL . Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy. Mol Ther 2014; 22: 123–131.
3. Bourke MG, Salwa S, Harrington KJ, Kucharczyk MJ, Forde PF, Kruijf de M et al. The emerging role of viruses in the treatment of solid tumours. Cancer Treat Rev 2011; 37: 618–632.
4. Aghi MK, Chiocca EA . Phase Ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication. Mol Ther 2009; 17: 8–9.
5. Hu JCC, Coffin RS, Davis CJ, Graham NJ, Groves N, Guest PJ et al. A phase I study of OncoVEX(GM-CSF), a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res 2006; 12: 6737–6747.
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