Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma-Reference-Cited by-同舟云学术

Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma

Published:2018-10 Issue:9 Volume:119 Page:1118-1128
ISSN:0007-0920
Container-title:British Journal of Cancer
language:en
Short-container-title:Br J Cancer

Author:

Al-Saffar Nada M. S.,Troy Helen,Wong Te Fong Anne-Christine,Paravati Roberta,Jackson L. Elizabeth,Gowan Sharon,Boult Jessica K. R.,Robinson Simon P.,Eccles Suzanne A.,Yap Timothy A.,Leach Martin O.,Chung Yuen-Li

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

http://www.nature.com/articles/s41416-018-0242-3.pdf

Reference48 articles.

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3. Khan, K. H., Yap, T. A., Yan, L. & Cunningham, D. Targeting the PI3K-AKT-mTOR signaling network in cancer. Chin. J. Cancer 32, 253–265 (2013).

4. Nitulescu, G. M. et al. Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review). Int. J. Oncol. 48, 869–885 (2016).

5. Ahn, D. H. et al. Results of an abbreviated phase-II study with the Akt inhibitor MK-2206 in patients with advanced biliary cancer. Sci. Rep. 5, 12122 (2015).

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