Large cell neuroendocrine lung carcinoma: consensus statement from The British Thoracic Oncology Group and the Association of Pulmonary Pathologists-Reference-Cited by-同舟云学术

Large cell neuroendocrine lung carcinoma: consensus statement from The British Thoracic Oncology Group and the Association of Pulmonary Pathologists

Published:2021-09-06 Issue:9 Volume:125 Page:1210-1216
ISSN:0007-0920
Container-title:British Journal of Cancer
language:en
Short-container-title:Br J Cancer

Author:

Lindsay Colin R.,Shaw Emily C.,Moore David A.,Rassl Doris,Jamal-Hanjani Mariam,Steele Nicola,Naheed Salma,Dick Craig,Taylor Fiona,Adderley Helen,Black Fiona,Summers Yvonne,Evans Matt,Rice Alexandra,Fabre Aurelie,Wallace William A.,Nicholson Siobhan,Haragan Alex,Taniere Phillipe,Nicholson Andrew G.,Laing Gavin,Cave Judith,Forster Martin D.,Blackhall Fiona,Gosney John,Popat Sanjay^ORCID,Kerr Keith M.

Abstract

AbstractOver the past 10 years, lung cancer clinical and translational research has been characterised by exponential progress, exemplified by the introduction of molecularly targeted therapies, immunotherapy and chemo-immunotherapy combinations to stage III and IV non-small cell lung cancer. Along with squamous and small cell lung cancers, large cell neuroendocrine carcinoma (LCNEC) now represents an area of unmet need, particularly hampered by the lack of an encompassing pathological definition that can facilitate real-world and clinical trial progress. The steps we have proposed in this article represent an iterative and rational path forward towards clinical breakthroughs that can be modelled on success in other lung cancer pathologies.

Funder

Cancer Research UK

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

https://www.nature.com/articles/s41416-021-01407-9.pdf

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