Enhanced antitumor effect of binimetinib in combination with capecitabine for biliary tract cancer patients with mutations in the RAS/RAF/MEK/ERK pathway: phase Ib study-Reference-Cited by-同舟云学术

Enhanced antitumor effect of binimetinib in combination with capecitabine for biliary tract cancer patients with mutations in the RAS/RAF/MEK/ERK pathway: phase Ib study

Published:2019-07-17 Issue:4 Volume:121 Page:332-339
ISSN:0007-0920
Container-title:British Journal of Cancer
language:en
Short-container-title:Br J Cancer

Author:

Kim Jin Won^ORCID,Lee Kyung-Hun,Kim Ji-Won,Suh Koung Jin,Nam Ah-Rong,Bang Ju-Hee,Bang Yung-Jue,Oh Do-Youn

Funder

Seoul National University Hospital

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

http://www.nature.com/articles/s41416-019-0523-5.pdf

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3. Lamarca, A., Hubner, R. A., David Ryder, W. & Valle, J. W. Second-line chemotherapy in advanced biliary cancer: a systematic review. Ann. Oncol. 25, 2328–2338 (2014).

4. Nakamura, H., Arai, Y., Totoki, Y., Shirota, T., Elzawahry, A., Kato, M. et al. Genomic spectra of biliary tract cancer. Nat. Genet. 47, 1003–1010 (2015).

5. Tannapfel, A., Sommerer, F., Benicke, M., Katalinic, A., Uhlmann, D., Witzigmann, H. et al. Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma. Gut. 52, 706–712 (2003).

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