Abstract
AbstractThe NHS Long Term Plan for cancer aims to increase early-stage diagnoses from 50% to 75% and to have 55,000 more people each year survive their cancer for at least 5 years following diagnosis. The targets measures are flawed and could be met without improving outcomes that really matter to patients. The proportion of early-stage diagnoses could increase, while the number of patients presenting at a late-stage remains the same. More patients could survive their cancer for longer, but lead time and overdiagnosis bias make it impossible to know whether anyone had their life prolonged. The target measures should switch from biased case-based measures to unbiased population-based measures that reflect the key objectives in cancer care: reducing late-stage incidence and mortality.
Publisher
Springer Science and Business Media LLC
Reference31 articles.
1. Gov.UK. Government announces plans for earlier diagnosis for cancer patients. 2018. https://www.gov.uk/government/news/government-announces-plans-for-earlier-diagnosis-for-cancer-patients.
2. Hellman S. Karnofsky Memorial Lecture. Natural history of small breast cancers. J Clin Oncol. 1994;12:2229–34.
3. Breslow L, Bailar JC, Brown BW, Brown HG, Darity WA, Defendi V, et al. Measurement of progress against cancer. Extramural Committee to Assess Measures of Progress Against Cancer. J Natl Cancer Inst. 1990;82:825–35.
4. Travis K. Bernard Fisher reflects on a half-century’s worth of breast cancer research. J Natl Cancer Inst. 2005;97:1636–7.
5. Hu Z, Ding J, Ma Z, Sun R, Seoane JA, Scott Shaffer J, et al. Quantitative evidence for early metastatic seeding in colorectal cancer. Nat Genet. 2019;51:1113–22.
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