Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
https://www.nature.com/articles/s41416-022-02080-2.pdf
Reference5 articles.
1. Green HD, Merriel SWD, Oram RA, Ruth KS, Tyrrell J, Jones SE et al. Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank. Br J Cancer. 2022. https://doi.org/10.1038/s41416-022-01918-z.
2. NICE. Lower urinary tract symptoms in men: management [CG97]. 2010. https://www.nice.org.uk/guidance/cg97/chapter/Recommendations.
3. Klein RJ, Vertosick E, Sjoberg D, Ulmert D, Rönn AC, Häggström C, et al. Prostate cancer polygenic risk score and prediction of lethal prostate cancer. NPJ Precis Oncol. 2022;6:25.
4. Hoffman RM, Gilliland FD, Eley JW, Harlan LC, Stephenson RA, Stanford JL, et al. Racial and ethnic differences in advanced-stage prostate cancer: the Prostate Cancer Outcomes Study. J Natl Cancer Inst. 2001;93:388–95.
5. Yamoah K, Lee KM, Awasthi S, Alba PR, Perez C, Anglin-Foote TR, et al. Racial and Ethnic Disparities in Prostate Cancer Outcomes in the Veterans Affairs Health Care System. JAMA Netw Open. 2022;5:e2144027.
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