Phospholipase Cγ1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE-Reference-Cited by-同舟云学术

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Phospholipase Cγ1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE

Published:2002-01 Issue:6871 Volume:415 Page:541-544
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Ye Keqiang,Aghdasi Bahman,Luo Hongbo R.,Moriarity John L.,Wu Frederick Y.,Hong Jenny J.,Hurt K. Joseph,Bae Sun Sik,Suh Pann-Ghill,Snyder Solomon H.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/415541a.pdf

Reference28 articles.

1. Bae, S. S. et al. Src homology domains of phospholipase Cγ1 inhibit nerve growth factor-induced differentiation of PC12 cells. J. Neurochem. 71, 178–185 (1998).

2. Smith, M. R. et al. Overexpression of phosphoinositide-specific phospholipase Cγ in NIH 3T3 cells promotes transformation and tumorigenicity. Carcinogenesis 19, 177–185 (1998).

3. Smith, M. R. et al. Phospholipase C-γ1 can induce DNA synthesis by a mechanism independent of its lipase activity. Proc. Natl Acad. Sci. USA 91, 6554–6558 (1994).

4. Huang, P. S. et al. An SH3 domain is required for the mitogenic activity of microinjected phospholipase C-γ1. FEBS Lett. 358, 287–292 (1995).

5. Ye, K. et al. Pike. A nuclear gtpase that enhances PI3 kinase activity and is regulated by protein 4.1N. Cell 103, 919–930 (2000).

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