Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/nchem.2591.pdf
Reference45 articles.
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3. Hopper, J. T. & Robinson, C. V. Mass spectrometry quantifies protein interactions—from molecular chaperones to membrane porins. Angew. Chem. Int. Ed. 53, 14002–14015 (2014).
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5. Avci, D. & Lemberg, M. K. Clipping or extracting: two ways to membrane protein degradation. Trends Cell Biol. 25, 611–622 (2015).
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