The roles of RNA processing in translating genotype to phenotype
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm.2016.139.pdf
Reference142 articles.
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3. Li, Y. I. et al. RNA splicing is a primary link between genetic variation and disease. Science 352, 600–604 (2016). A systematic analysis of LCLs from 68 individuals identified genomic variants that correlate with differences in up to eight molecular features of the gene regulatory cascade.
4. Lappalainen, T. et al. Transcriptome and genome sequencing uncovers functional variation in humans. Nature 501, 506–511 (2013). This study identified the genomic causes of variation in the transcriptome using RNA-seq and genomic sequence data from LCLs of 462 individuals in the 1000 Genomes Project.
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