Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma-Reference-Cited by-同舟云学术

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Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma

Published:2008-08-28 Issue:3 Volume:23 Page:585-590
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Mao X,Li X,Sprangers R,Wang X,Venugopal A,Wood T,Zhang Y,Kuntz D A,Coe E,Trudel S,Rose D,Batey R A,Kay L E,Schimmer A D

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/leu2008232.pdf

Reference8 articles.

1. Lowe J, Stock D, Jap B, Zwickl P, Baumeister W, Huber R . Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science 1995; 268: 533–539.

2. Richardson PG, Sonneveld P, Schuster MW, Irwin D, Stadtmauer EA, Facon T et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 2005; 352: 2487–2498.

3. Fisher RI, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S et al. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol 2006; 24: 4867–4874.

4. Groll M, Berkers CR, Ploegh HL, Ovaa H . Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome. Structure 2006; 14: 451–456.

5. Chen D, Cui QC, Yang H, Barrea RA, Sarkar FH, Sheng S et al. Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts. Cancer Res 2007; 67: 1636–1644.

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