A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization-Reference-Cited by-同舟云学术

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization

Published:2013-09-08 Issue:10 Volume:20 Page:1191-1198
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Jeyasekharan Anand D,Liu Yang,Hattori Hiroyoshi,Pisupati Venkat,Jonsdottir Asta Bjork,Rajendra Eeson,Lee Miyoung,Sundaramoorthy Elayanambi,Schlachter Simon,Kaminski Clemens F,Ofir-Rosenfeld Yaara,Sato Ko,Savill Jane,Ayoub Nabieh,Venkitaraman Ashok R

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsmb.2666.pdf

Reference56 articles.

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3. King, T.A. et al. Heterogenic loss of the wild-type BRCA allele in human breast tumorigenesis. Ann. Surg. Oncol. 14, 2510–2518 (2007).

4. Knudson, A.G. Jr. Mutation and cancer: statistical study of retinoblastoma. Proc. Natl. Acad. Sci. USA 68, 820–823 (1971).

5. Skoulidis, F. et al. Germline Brca2 heterozygosity promotes KrasG12D-driven carcinogenesis in a murine model of familial pancreatic cancer. Cancer Cell 18, 499–509 (2010).

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