Sequential exo-mode oxacyclizations for the synthesis of the CD substructure of brevenal
Author:
Funder
National Science Foundation
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
http://www.nature.com/articles/s41429-018-0124-1.pdf
Reference34 articles.
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2. Fuwa H, Ebine M, Bourdelais AJ, Baden DG, Sasaki M. Total synthesis, structure revision, and absolute configuration of (-)-brevenal. J Am Chem Soc. 2006;128:16989–99.
3. Yasumoto T, Murata M. Marine Toxins. Chem Rev. 1993;93:1897–909.
4. Bourdelais AJ, et al. Brevenal is a natural inhibitor of brevetoxin action in sodium channel receptor binding assays. Cell Mol Neurobiol. 2004;24:553–63.
5. Gold EP, Jacocks HM, Bourdelais AJ, Baden DG. Brevenal, a brevetoxin antagonist from Karenia brevis, binds to a previously unreported site on mammalian sodium channels. Harmful Algae. 2013;26:12–19.
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