4-O-Methylascochlorin inhibits the prolyl hydroxylation of hypoxia-inducible factor-1α, which is attenuated by ascorbate-Reference-Cited by-同舟云学术

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4-O-Methylascochlorin inhibits the prolyl hydroxylation of hypoxia-inducible factor-1α, which is attenuated by ascorbate

Published:2019-02-22 Issue:5 Volume:72 Page:271-281
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Kondo Tetsuya,Takeda Kenji,Muko Ryo,Ito Akihiro,Chang Young-Chae,Magae Junji,Kataoka Takao

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

https://www.nature.com/articles/s41429-019-0157-0.pdf

Reference52 articles.

1. Semenza GL. Hypoxia-inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype. EMBO J. 2017;36:252–9.

2. Majmundar AJ, Wong WJ, Simon MC. Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell. 2010;40:294–309.

3. Semenza GL. Hypoxia-inducible factors in physiology and medicine. Cell. 2012;148:399–408.

4. Bertout JA, Patel SA, Simon MC. The impact of O2 availability on human cancer. Nat Rev Cancer. 2008;8:967–75.

5. Weidemann A, Johnson RS. Biology of HIF-1α. Cell Death Differ. 2008;15:621–7.

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1. The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway;Scientific Reports;2023-08-28

2. Allantopyrone A interferes with the degradation of hypoxia-inducible factor 1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells;The Journal of Antibiotics;2023-03-30

3. 4-O-Methylascochlorin-Mediated BNIP-3 Expression Controls the Balance of Apoptosis and Autophagy in Cervical Carcinoma Cells;International Journal of Molecular Sciences;2022-12-01

4. Cucurbitacin B Down-Regulates TNF Receptor 1 Expression and Inhibits the TNF-α-Dependent Nuclear Factor κB Signaling Pathway in Human Lung Adenocarcinoma A549 Cells;International Journal of Molecular Sciences;2022-06-27

5. 4-O-methylascochlorin-stimulated HIF-1α expression induces the epithelial mesenchymal transition and cell survival in breast cancer cells;Toxicology in Vitro;2022-06

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