Potent Dual Inhibitors of TORC1 and TORC2 Complexes (KU-0063794 and KU-0068650) Demonstrate In Vitro and Ex Vivo Anti-Keloid Scar Activity
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Dermatology,Molecular Biology,Biochemistry
Reference35 articles.
1. Long-term organ culture of keloid disease tissue;Bagabir;Exp Dermatol,2012
2. Rapamycin passes the torch: a new generation of mTOR inhibitors;Benjamin;Nat Rev Drug Discov,2011
3. mTORC1-and mTORC2-interacting proteins keep their multifunctional partners focused;Bracho-Valdes;IUBMB Life,2011
4. Dual inhibition of PI3K and mTORC1/2 signaling by NVP-BEZ235 as a new therapeutic strategy for acute myeloid leukemia;Chapuis;Clin Cancer Res,2010
5. AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity;Chresta;Cancer Res,2010
Cited by 36 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Pharmacological effects of mTORC1/C2 inhibitor in a preclinical model of NASH progression;Biomedicine & Pharmacotherapy;2023-11
2. Regulation of Eukaryotic Translation Initiation Factor 4E as a Potential Anticancer Strategy;Journal of Medicinal Chemistry;2023-09-19
3. Roles of the HIF-1α pathway in the development and progression of keloids;Heliyon;2023-08
4. The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds;Cells;2023-06-20
5. UCHL1 aggravates skin fibrosis through an IGF‐1‐induced Akt/mTOR/HIF‐1α pathway in keloid;The FASEB Journal;2023-05-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3