Polyglutamine expansion of huntingtin impairs its nuclear export
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://www.nature.com/articles/ng1503.pdf
Reference29 articles.
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2. Sugars, K.L. & Rubinsztein, D.C. Transcriptional abnormalities in Huntington disease. Trends Genet. 19, 233–238 (2003).
3. DiFiglia, M. et al. Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron 14, 1075–1081 (1995).
4. Sharp, A.H. et al. Widespread expression of Huntington's disease gene (IT15) protein product. Neuron 14, 1065–1074 (1995).
5. Gutekunst, C.A. et al. Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies. Proc. Natl. Acad. Sci. USA 92, 8710–8714 (1995).
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