Prospective functional classification of all possible missense variants in PPARG-Reference-Cited by-同舟云学术

Prospective functional classification of all possible missense variants in PPARG

Published:2016-10-17 Issue:12 Volume:48 Page:1570-1575
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Majithia Amit R, ,Tsuda Ben,Agostini Maura,Gnanapradeepan Keerthana,Rice Robert,Peloso Gina,Patel Kashyap A,Zhang Xiaolan,Broekema Marjoleine F^ORCID,Patterson Nick,Duby Marc,Sharpe Ted,Kalkhoven Eric,Rosen Evan D,Barroso Inês^ORCID,Ellard Sian,Kathiresan Sekar,O'Rahilly Stephen^ORCID,Chatterjee Krishna,Florez Jose C,Mikkelsen Tarjei^ORCID,Savage David B,Altshuler David, ,

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng.3700.pdf

Reference30 articles.

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4. Jeninga, E.H., Gurnell, M. & Kalkhoven, E. Functional implications of genetic variation in human PPARγ. Trends Endocrinol. Metab. 20, 380–387 (2009).

5. Majithia, A.R. et al. Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Proc. Natl. Acad. Sci. USA 111, 13127–13132 (2014).

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