3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained-Reference-Cited by-同舟云学术

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3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

Published:2016-01-11 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Zanoni Michele,Piccinini Filippo,Arienti Chiara,Zamagni Alice,Santi Spartaco,Polico Rolando,Bevilacqua Alessandro,Tesei Anna

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep19103.pdf

Reference42 articles.

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2. Ocana, A., Pandiella, A., Siu, L. L. & Tannock, I. F. Preclinical development of molecular-targeted agents for cancer. Nat. Rev. Clin. Oncol. 8, 200–209 (2010).

3. Sams-Dodd, F. Target-based drug discovery: is something wrong? Drug Discov. Today 10, 139–147 (2005).

4. Edwards, A. M. et al. Preclinical target validation using patient-derived cells. Nat. Rev. Drug Discov. 14, 149–150 (2015).

5. Lee, G. Y., Kenny, P. A., Lee, E. H. & Bissell, M. J. Three-dimensional culture models of normal and malignant breast epithelial cells. Nat. Methods 4, 359–365 (2007).

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