Exome-wide association study of plasma lipids in >300,000 individuals
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Published:2017-10-30
Issue:12
Volume:49
Page:1758-1766
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Liu Dajiang J, , Peloso Gina M, Yu Haojie, Butterworth Adam S, Wang Xiao, Mahajan Anubha, Saleheen Danish, Emdin Connor, Alam Dewan, Alves Alexessander Couto, Amouyel Philippe, Di Angelantonio Emanuele, Arveiler Dominique, Assimes Themistocles L, Auer Paul L, Baber Usman, Ballantyne Christie M, Bang Lia E, Benn Marianne, Bis Joshua C, Boehnke Michael, Boerwinkle Eric, Bork-Jensen Jette, Bottinger Erwin P, Brandslund Ivan, Brown Morris, Busonero Fabio, Caulfield Mark J, Chambers John C, Chasman Daniel I, Chen Y Eugene, Chen Yii-Der Ida, Chowdhury Rajiv, Christensen Cramer, Chu Audrey Y, Connell John M, Cucca Francesco, Cupples L Adrienne, Damrauer Scott M, Davies Gail, Deary Ian J, Dedoussis George, Denny Joshua C, Dominiczak Anna, Dubé Marie-Pierre, Ebeling Tapani, Eiriksdottir Gudny, Esko Tõnu, Farmaki Aliki-Eleni, Feitosa Mary F, Ferrario Marco, Ferrieres Jean, Ford Ian, Fornage Myriam, Franks Paul W, Frayling Timothy M, Frikke-Schmidt Ruth, Fritsche Lars G, Frossard Philippe, Fuster Valentin, Ganesh Santhi K, Gao Wei, Garcia Melissa E, Gieger Christian, Giulianini Franco, Goodarzi Mark O, Grallert Harald, Grarup Niels, Groop Leif, Grove Megan L, Gudnason Vilmundur, Hansen Torben, Harris Tamara B, Hayward Caroline, Hirschhorn Joel N, Holmen Oddgeir L, Huffman Jennifer, Huo Yong, Hveem Kristian, Jabeen Sehrish, Jackson Anne U, Jakobsdottir Johanna, Jarvelin Marjo-Riitta, Jensen Gorm B, Jørgensen Marit E, Jukema J Wouter, Justesen Johanne M, Kamstrup Pia R, Kanoni Stavroula, Karpe Fredrik, Kee Frank, Khera Amit V, Klarin Derek, Koistinen Heikki A, Kooner Jaspal S, Kooperberg Charles, Kuulasmaa Kari, Kuusisto Johanna, Laakso Markku, Lakka Timo, Langenberg Claudia, Langsted Anne, Launer Lenore J, Lauritzen Torsten, Liewald David C M, Lin Li An, Linneberg Allan, Loos Ruth J F, Lu Yingchang, Lu Xiangfeng, Mägi Reedik, Malarstig Anders, Manichaikul Ani, Manning Alisa K, Mäntyselkä Pekka, Marouli Eirini, Masca Nicholas G D, Maschio Andrea, Meigs James B, Melander Olle, Metspalu Andres, Morris Andrew P, Morrison Alanna C, Mulas Antonella, Müller-Nurasyid Martina, Munroe Patricia B, Neville Matt J, Nielsen Jonas BORCID, Nielsen Sune F, Nordestgaard Børge G, Ordovas Jose M, Mehran Roxana, O'Donnell Christoper J, Orho-Melander Marju, Molony Cliona M, Muntendam Pieter, Padmanabhan Sandosh, Palmer Colin N A, Pasko Dorota, Patel Aniruddh P, Pedersen Oluf, Perola Markus, Peters Annette, Pisinger Charlotta, Pistis Giorgio, Polasek Ozren, Poulter Neil, Psaty Bruce M, Rader Daniel J, Rasheed Asif, Rauramaa Rainer, Reilly Dermot F, Reiner Alex P, Renström Frida, Rich Stephen S, Ridker Paul M, Rioux John D, Robertson Neil R, Roden Dan M, Rotter Jerome I, Rudan Igor, Salomaa Veikko, Samani Nilesh J, Sanna Serena, Sattar Naveed, Schmidt Ellen M, Scott Robert A, Sever Peter, Sevilla Raquel S, Shaffer Christian M, Sim Xueling, Sivapalaratnam Suthesh, Small Kerrin S, Smith Albert V, Smith Blair H, Somayajula Sangeetha, Southam Lorraine, Spector Timothy D, Speliotes Elizabeth K, Starr John M, Stirrups Kathleen E, Stitziel Nathan, Strauch Konstantin, Stringham Heather M, Surendran Praveen, Tada Hayato, Tall Alan R, Tang Hua, Tardif Jean-Claude, Taylor Kent D, Trompet Stella, Tsao Philip S, Tuomilehto Jaakko, Tybjaerg-Hansen Anne, van Zuydam Natalie R, Varbo Anette, Varga Tibor V, Virtamo Jarmo, Waldenberger Melanie, Wang Nan, Wareham Nick J, Warren Helen R, Weeke Peter E, Weinstock Joshua, Wessel Jennifer, Wilson James G, Wilson Peter W F, Xu Ming, Yaghootkar Hanieh, Young Robin, Zeggini Eleftheria, Zhang He, Zheng Neil S, Zhang Weihua, Zhang Yan, Zhou Wei, Zhou Yanhua, Zoledziewska Magdalena, Howson Joanna M M, Danesh John, McCarthy Mark I, Cowan Chad A, Abecasis Goncalo, Deloukas Panos, Musunuru Kiran, Willer Cristen J, Kathiresan SekarORCID, , , ,
Publisher
Springer Science and Business Media LLC
Reference52 articles.
1. Teslovich, T.M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707–713 (2010). 2. Asselbergs, F.W. et al. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am. J. Hum. Genet. 91, 823–838 (2012). 3. Willer, C.J. et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 45, 1274–1283 (2013). 4. Albrechtsen, A. et al. Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia 56, 298–310 (2013). 5. Peloso, G.M. et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am. J. Hum. Genet. 94, 223–232 (2014).
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