Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase γ-Reference-Cited by-同舟云学术

Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase γ

Published:2007-02-19 Issue:4 Volume:87 Page:326-335
ISSN:0023-6837
Container-title:Laboratory Investigation
language:en
Short-container-title:Lab Invest

Author:

Lewis William,Day Brian J,Kohler James J,Hosseini Seyed H,Chan Sherine S L,Green Elgin C,Haase Chad P,Keebaugh Erin S,Long Robert,Ludaway Tomika,Russ Rodney,Steltzer Jeffrey,Tioleco Nina,Santoianni Robert,Copeland William C

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Pathology and Forensic Medicine

Link

http://www.nature.com/articles/3700523.pdf

Reference51 articles.

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3. Lim SE, Longley MJ, Copeland WC . The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance. J Biol Chem 1999;274:38197–38203.

4. Longley MJ, Nguyen D, Kunkel TA, et al. The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit. J Biol Chem 2001;276:38555–38562.

5. Trifunovic A, Wredenberg A, Falkenberg M, et al. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 2004;429:417–423.

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