FTY720, a sphingosine 1-phosphate receptor modulator, inhibits CD1d-restricted NKT cells by suppressing cytokine production but not migration-Reference-Cited by-同舟云学术

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FTY720, a sphingosine 1-phosphate receptor modulator, inhibits CD1d-restricted NKT cells by suppressing cytokine production but not migration

Published:2009-10-12 Issue:1 Volume:90 Page:9-19
ISSN:0023-6837
Container-title:Laboratory Investigation
language:en
Short-container-title:Lab Invest

Author:

Hwang Su Jin,Kim Ji Hyung,Kim Hye Young,Kim Sanghee,Chung Doo Hyun

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Pathology and Forensic Medicine

Link

http://www.nature.com/articles/labinvest2009109.pdf

Reference55 articles.

1. Taniguchi M, Harada M, Kojo S, et al. The regulatory role of Vα14 NKT cells in innate and acquired immune response. Annu Rev Immunol 2003;21:483–513.

2. Lantz O, Bendelac A . An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4−8− T cells in mice and humans. J Exp Med 1994;180:1097–1106.

3. Bendelac A . CD1: presenting unusual antigens to unusual T lymphocytes. Science 1995;269:185–186.

4. Kim HY, Kim HJ, Min HS, et al. NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor β1 production. J Exp Med 2005;201:41–47.

5. Kim HJ, Hwang SJ, Kim BK, et al. NKT cells play critical roles in the induction of oral tolerance by inducing regulatory T cells producing IL-10 and transforming growth factor beta, and by clonally deleting antigen-specific T cells. Immunology 2006;118:101–111.

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